Role of cholesterol in cognitive function in the elderly

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Original Article

Author Details : Vishwin Doda, V K Deshpande*

Volume : 8, Issue : 2, Year : 2021

Article Page : 56-59

https://doi.org/10.18231/j.agems.2021.013

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Abstract

Background & Aim: The role of cholesterol in Cognitive Decline is less known as compared to other pathologies linked with dyslipidaemia. However, Cholesterol is well-known to have multiple functions in normal functioning of the brain and the aging process. This study therefore aimed at finding a co-relation, if any, between Cholesterol and age-related cognitive decline.
Objective: To assess Cognitive Function of subjects and compare it with respective blood cholesterol levels.
Material and Methods: The study included 50 elderly subjects from Maharashtra (females: 12%) assessed using Marathi version of Mini Mental State Examination (MMSE) and their cholesterol blood concentrations obtained using a Lipid Profile investigation. Cholesterol levels and cognitive function was then co-related using statistical analysis.
Results: The subjects with a higher Total Cholesterol & LDL Cholesterol had slightly less scores on the Mini Mental State Examination (MMSE) Test. However, the difference was found to be significant.
Conclusion: Based on the results obtained, no relevant co-relation could be found between Blood Cholesterol Levels and Cognitive Function

Keywords: Cognition, Cognitive decline, Mini mental state examination, Lipid, Dyslipidemia

How to cite : Doda V, Deshpande V K, Role of cholesterol in cognitive function in the elderly. Ann Geriatr Educ Med Sci 2021;8(2):56-59

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